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Target
Kallikrein-7
Ligand
BDBM50355087
Substrate
n/a
Meas. Tech.
ChEMBL_772792 (CHEMBL1837531)
IC50
165800±n/a nM
Citation
 Teixeira, TS; Freitas, RF; Abrahão, O; Devienne, KF; de Souza, LR; Blaber, SI; Blaber, M; Kondo, MY; Juliano, MA; Juliano, L; Puzer, L Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7. Bioorg Med Chem Lett 21:6112-5 (2011) [PubMed]  Article 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM50355087
Synonyms:
CHEMBL1833982
Type:
Small organic molecule
Emp. Form.:
C16H14O6
Mol. Mass.:
302.2788
SMILES:
COc1cc(O)c2c(O)c3c(cc(C)oc3=O)c(OC)c2c1
Structure:
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