Reaction Details Report a problem with these data
Target
Isocitrate lyase
Ligand
BDBM50358281
Substrate
n/a
Meas. Tech.
ChEMBL_790943 (CHEMBL1925559)
IC50
20700±n/a nM
Citation
 Bouthenet, E; Oh, KB; Park, S; Nagi, NK; Lee, HS; Matthews, SE Synthesis and antimicrobial activity of brominated resorcinol dimers. Bioorg Med Chem Lett 21:7142-5 (2011) [PubMed]  Article 
Target
Name:
Isocitrate lyase
Synonyms:
ACEA_CANAX | ICL1
Type:
PROTEIN
Mol. Mass.:
61398.95
Organism:
Candida albicans
Description:
ChEMBL_972063
Residue:
550
Sequence:
MPYTPIDIQKEEADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQADKLFKLLETHDADKTVSFTFGALDPIHVAQMAKYLDSIYVSGWQCSSTASTSNEPSPDLADYPMDTVPNKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGITAIIKLTKMFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGSNLLAVARTDSEAATLITSTIDHRDHYFIIGATNPEAGDLAALMAEAESKGIYGNELAAIESEWTKKAGLKLFHEAVIDEIKNGNYSNKDALIKKFTDKVNPLSHTSHKEAKKLAKELTGKDIYFNWDVARAREGYYRYQGGTQCAVMRGRAFAPYADLIWMESALPDYAQAKEFADGVKAAVPDQWLAYNLSPSFNWNKAMPADEQETYIKRLGKLGYVWQFITLAGLHTTALAVDDFSNQYSQIGMKAYGQTVQQPEIEKGVEVVKHQKWSGATYIDGLLKMVSGGVTSTAAMGQGVTEDQFKESKAKA
  
Inhibitor
Name:
BDBM50358281
Synonyms:
CHEMBL1922397
Type:
Small organic molecule
Emp. Form.:
C19H13Br2NO6
Mol. Mass.:
511.118
SMILES:
Oc1cc(O)c(cc1Br)C(c1ccc(cc1)[N+]([O-])=O)c1cc(Br)c(O)cc1O
Structure:
Search PDB for entries with ligand similarity: