Reaction Details Report a problem with these data
Target
ATP-dependent Clp protease proteolytic subunit
Ligand
BDBM50360279
Substrate
n/a
Meas. Tech.
ChEMBL_796596 (CHEMBL1937911)
EC50
3400±n/a nM
Citation
Zeiler, E; Korotkov, VS; Lorenz-Baath, K; Böttcher, T; Sieber, SA Development and characterization of improvedß-lactone-based anti-virulence drugs targeting ClpP. Bioorg Med Chem 20:583-91 (2012) [PubMed] Article
More Info.:
Target
Name:
ATP-dependent Clp protease proteolytic subunit
Synonyms:
CLPP_STAA8 | Endopeptidase Clp | clpP
Type:
PROTEIN
Mol. Mass.:
21508.79
Organism:
Staphylococcus aureus (strain NCTC 8325)
Description:
ChEMBL_796596
Residue:
195
Sequence:
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK