Reaction Details Report a problem with these data
Target
Melanin-concentrating hormone receptor 2
Ligand
BDBM50360683
Substrate
n/a
Meas. Tech.
ChEMBL_795933 (CHEMBL1936806)
Ki
13±n/a nM
Citation
 Chen, X; Mihalic, J; Fan, P; Liang, L; Lindstrom, M; Wong, S; Ye, Q; Fu, Y; Jaen, J; Chen, JL; Dai, K; Li, L Discovery and characterization of a potent and selective antagonist of melanin-concentrating hormone receptor 2. Bioorg Med Chem Lett 22:363-6 (2011) [PubMed]  Article 
Target
Name:
Melanin-concentrating hormone receptor 2
Synonyms:
GPR145 | MCHR2 | MCHR2_HUMAN | Melanin Concentrating Hormone 2 | Melanin-concentrating hormone receptor | Melanin-concentrating hormone receptor 2 | SLT
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38862.16
Organism:
Homo sapiens (Human)
Description:
Melanin Concentrating Hormone 2 GPR145 HUMAN::Q969V1
Residue:
340
Sequence:
MNPFHASCWNTSAELLNKSWNKEFAYQTASVVDTVILPSMIGIICSTGLVGNILIVFTIIRSRKKTVPDIYICNLAVADLVHIVGMPFLIHQWARGGEWVFGGPLCTIITSLDTCNQFACSAIMTVMSVDRYFALVQPFRLTRWRTRYKTIRINLGLWAASFILALPVWVYSKVIKFKDGVESCAFDLTSPDDVLWYTLYLTITTFFFPLPLILVCYILILCYTWEMYQQNKDARCCNPSVPKQRVMKLTKMVLVLVVVFILSAAPYHVIQLVNLQMEQPTLAFYVGYYLSICLSYASSSINPFLYILLSGNFQKRLPQIQRRATEKEINNMGNTLKSHF
  
Inhibitor
Name:
BDBM50360683
Synonyms:
CHEMBL1934130
Type:
Small organic molecule
Emp. Form.:
C29H30N4O2
Mol. Mass.:
466.5741
SMILES:
CC(=O)N[C@@H]1CC2(CCN(Cc3ccc4n(C(N)=O)c5ccccc5c4c3)CC2)c2ccccc12 |r|
Structure:
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