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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50076963
Substrate
n/a
Meas. Tech.
ChEBML_33962
Ki
5300000±n/a nM
Citation
 Dumas, DP; Kajimoto, T; Liu, KK; Wong, C; Berkowitz, DB; Danieshefsky, SJ Azasugar and glycal inhibitors of -L-fucosidase Bioorg Med Chem Lett 2:33-36 (1992)    Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase
Type:
PROTEIN
Mol. Mass.:
53690.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_34088
Residue:
466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50076963
Synonyms:
(3R,5R)-2-Hydroxymethyl-1-methyl-piperidine-3,4,5-triol | 2-Hydroxymethyl-1-methyl-piperidine-3,4,5-triol | CHEMBL418746
Type:
Small organic molecule
Emp. Form.:
C7H15NO4
Mol. Mass.:
177.1983
SMILES:
CN1CC(O)C(O)C(O)C1CO
Structure:
Search PDB for entries with ligand similarity: