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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50072588
Substrate
n/a
Meas. Tech.
ChEMBL_216279 (CHEMBL819885)
Ki
5.8±n/a nM
Citation
 Witczak, ZJ; Sun, J; Mielguj, R Synthesis of L-fucopyranosyl-4-thiodisaccharides from levoglucosenone and their inhibitory activity on -L-fucosidase Bioorg Med Chem Lett 5:2169-2174 (1995)    Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase
Type:
PROTEIN
Mol. Mass.:
53690.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_34088
Residue:
466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50072588
Synonyms:
(2S,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidine-3,4,5-triol | 2-hydroxymethyl-6-methyl-(2S,3R,4R,5R,6S)-hexahydro-3,4,5-pyridinetriol | CHEMBL69294
Type:
Small organic molecule
Emp. Form.:
C7H15NO4
Mol. Mass.:
177.1983
SMILES:
CC1NC(CO)[C@@H](O)[C@@H](O)[C@@H]1O
Structure:
Search PDB for entries with ligand similarity: