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TargetEDNRB
LigandBDBM50366419
Substrate/Competitorn/a
Meas. Tech.ChEBML_64047
IC50 13000±n/a nM
Citation Leonard, DMReily, MDDunbar, JBHolub, KECody, WLHill, KEWelch, KMFlynn, MAReynolds, EEDoherty, AM Structure-activity and biophysical studies of the C-terminal hexapeptide of endothelin Bioorg Med Chem Lett5:967-972 (1995)    Article
More Info.:Get all data from this article,  Assay Method
 
EDNRB
Name:Endothelin receptor
Synonyms:ENDOTHELIN B | ET-B | Endothelin receptor | Endothelin receptor non-selective type
Type:Enzyme Catalytic Domain
Mol. Mass.:49483.43
Organism:RAT
Description:ENDOTHELIN B EDNRB RAT::P21451
Residue:442
Sequence:
MQSSASRCGRALVALLLACGLLGVWGEKRGFPPAQATPSLLGTKEVMTPPTKTSWTRGSN
SSLMRSSAPAEVTKGGRVAGVPPRSFPPPCQRKIEINKTFKYINTIVSCLVFVLGIIGNS
TLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINAYKLLAGDWPFGAEMCKLVPFI
QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
DVITSDYKGKPLRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLAITAIFYTLMTCEM
LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQSNPQRCEL
LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQTFEEKQSLEEKQSC
LKFKANDHGYDNFRSSNKYSSS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50366419
NameBDBM50366419
Synonyms:CHEMBL2369710
TypeSmall organic molecule
Emp. Form.C43H58N8O9
Mol. Mass.830.9688
SMILESCC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
Structure
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