Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50450457
Substrate
n/a
Meas. Tech.
ChEBML_29594
EC50
0.810000±n/a nM
Citation
 Scammells, P; Baker, S; Bellardinelli, L; Olsson, R; Russell, R; Knevitt, S The design and synthesis of novel adenosine agonists Bioorg Med Chem Lett 6:811-814 (1996)    Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50450457
Synonyms:
CHEMBL2364570
Type:
Small organic molecule
Emp. Form.:
C17H21N5O5
Mol. Mass.:
375.3791
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@H]3CC4CC3C3OC43)ncnc12 |r,THB:14:15:20.22:18,21:20:18:15.16,21:22:18:15.16|
Structure:
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