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Target
D(3) dopamine receptor
Ligand
BDBM50054067
Substrate
n/a
Meas. Tech.
ChEBML_58772
Ki
0.600000±n/a nM
Citation
 Belliotti, TR; Kesten, SR; Rubin, JR; Wustrow, DJ; Georgic, LM; Zoski, KT; Akunne, HC; Wise, LD Novel cyclohexyl amides as potent and selective D3 dopamine receptor ligands Bioorg Med Chem Lett 7:2403-2408 (1997)    Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50054067
Synonyms:
(2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol | (7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium(R(+)7OH-DPAT) | (R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol | (R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol | (R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol.HCl | 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol | CHEMBL301559
Type:
Small organic molecule
Emp. Form.:
C16H25NO
Mol. Mass.:
247.3758
SMILES:
CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1
Structure:
Search PDB for entries with ligand similarity: