Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50450461
Substrate
n/a
Meas. Tech.
ChEBML_50195
IC50
1426±n/a nM
Citation
 Herrero, S; Suarez-Gea, M; Gonzalez-Muniz, R; Garcia-Lopez, M; Herranz, R; Ballaz, S; Barber, A; Fortuno, A; Del Rio, J Pseudopeptide CCK-4 analogues incorporating the [CH(CN)NH] peptide bond surrogate Bioorg Med Chem Lett 7:855-860 (1997)    Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50450461
Synonyms:
CHEMBL2367718
Type:
Small organic molecule
Emp. Form.:
C35H44N4O6
Mol. Mass.:
616.7471
SMILES:
[H][C@]12CC[C@@](C)([C@@H](C1)OC(=O)N[C@](C)(Cc1c[nH]c3ccccc13)C(=O)NC[C@H](NC(=O)CCC(O)=O)c1ccccc1)C2(C)C |TLB:8:6:3.2:43|
Structure:
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