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Target
Capsid scaffolding protein
Ligand
BDBM50082158
Substrate
n/a
Meas. Tech.
ChEBML_158969
IC50
940±n/a nM
Citation
 Smith, DG; Gribble, AD; Haigh, D; Ife, RJ; Lavery, P; Skett, P; Slingsby, BP; Stacey, R; Ward, RW; West, A The inhibition of human cytomegalovirus (hCMV) protease by hydroxylamine derivatives. Bioorg Med Chem Lett 9:3137-42 (1999) [PubMed]  Article 
Target
Name:
Capsid scaffolding protein
Synonyms:
APNG | Assemblin | Assembly protein | Capsid protein P40 | Human cytomegalovirus protease (HCMV Pr) | Human herpes virus 5 capsid protein P40 | Protease precursor | SCAF_HCMVA | UL80 | pPR
Type:
PROTEIN
Mol. Mass.:
73854.16
Organism:
Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)
Description:
ChEMBL_158958
Residue:
708
Sequence:
MTMDEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQGQGQPSLSVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRCDDVEAATSLSGSETTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKASVSPEAACDIKAASAERSGDSRSQAATPAAGARVPSSSPSPPVEPPSPVQPPALPASPSVLPAESPPSLSPSEPAEAASMSHPLSAAVPAATAPPGATVAGASPAVSSLAWPHDGVYLPKDAFFSLLGASRSAVPVMYPGAVAAPPSASPAPLPLPSYPASYGAPVVGYDQLAARHFADYVDPHYPGWGRRYEPAPSLHPSYPVPPPPSPAYYRRRDSPGGMDEPPSGWERYDGGHRGQSQKQHRHGGSGGHNKRRKETAAASSSSSDEDLSFPGEAEHGRARKRLKSHVNSDGGSGGHAGSNQQQQQRYDELRDAIHELKRDLFAARQSSTLLSAALPSAASSSPTTTTVCTPTGELTSGGGETPTALLSGGAKVAERAQAGVVNASCRLATASGSEAATAGPSTAGSSSCPASVVLAAAAAQAAAASQSPPKDMVDLNRRIFVAALNKLE
  
Inhibitor
Name:
BDBM50082158
Synonyms:
2-[4-(4-Hydroxymethyl-benzoyl)-benzyl]-5-methyl-thieno[2,3-d][1,3]oxazin-4-one | CHEMBL107357
Type:
Small organic molecule
Emp. Form.:
C22H17NO4S
Mol. Mass.:
391.44
SMILES:
Cc1csc2nc(Cc3ccc(cc3)C(=O)c3ccc(CO)cc3)oc(=O)c12
Structure:
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