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Target
Glucoamylase
Ligand
BDBM50403869
Substrate
n/a
Meas. Tech.
ChEBML_34270
Ki
64000±n/a nM
Citation
 Popowycz, F; Gerber-Lemaire, S; Demange, R; Rodriguez-García, E; Asenjo, AT; Robina, I; Vogel, P Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors. Bioorg Med Chem Lett 11:2489-93 (2001) [PubMed]  Article 
Target
Name:
Glucoamylase
Synonyms:
AMYG_ASPNG | GLAA
Type:
PROTEIN
Mol. Mass.:
68272.68
Organism:
Aspergillus niger
Description:
ChEMBL_34265
Residue:
640
Sequence:
MSFRSLLALSGLVCTGLANVISKRATLDSWLSNEATVARTAILNNIGADGAWVSGADSGIVVASPSTDNPDYFYTWTRDSGLVLKTLVDLFRNGDTSLLSTIENYISAQAIVQGISNPSGDLSSGAGLGEPKFNVDETAYTGSWGRPQRDGPALRATAMIGFGQWLLDNGYTSTATDIVWPLVRNDLSYVAQYWNQTGYDLWEEVNGSSFFTIAVQHRALVEGSAFATAVGSSCSWCDSQAPEILCYLQSFWTGSFILANFDSSRSGKDANTLLGSIHTFDPEAACDDSTFQPCSPRALANHKEVVDSFRSIYTLNDGLSDSEAVAVGRYPEDTYYNGNPWFLCTLAAAEQLYDALYQWDKQGSLEVTDVSLDFFKALYSDAATGTYSSSSSTYSSIVDAVKTFADGFVSIVETHAASNGSMSEQYDKSDGEQLSARDLTWSYAALLTANNRRNSVVPASWGETSASSVPGTCAATSAIGTYSSVTVTSWPSIVATGGTTTTATPTGSGSVTSTSKTTATASKTSTSTSSTSCTTPTAVAVTFDLTATTTYGENIYLVGSISQLGDWETSDGIALSADKYTSSDPLWYVTVTLPAGESFEYKFIRIESDDSVEWESDPNREYTVPQACGTSTATVTDTWR
  
Inhibitor
Name:
BDBM50403869
Synonyms:
CHEMBL2115197
Type:
Small organic molecule
Emp. Form.:
C6H13NO2
Mol. Mass.:
131.1729
SMILES:
CC[C@H]1NC[C@H](O)[C@@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: