Reaction Details Report a problem with these data
Target
Adenylate kinase 4, mitochondrial
Ligand
BDBM50010316
Substrate
n/a
Meas. Tech.
ChEBML_32194
Ki
4800000±n/a nM
Citation
 Hampton, A; Picker, D; Nealy, KA; Maeda, M Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 4. Interactions of adenosine 5'-triphosphate derivatives with adenylate kinases from Escherichia coli and rat tissues. J Med Chem 25:382-6 (1982) [PubMed]  Article 
Target
Name:
Adenylate kinase 4, mitochondrial
Synonyms:
AK3 | AK3L1 | AK4 | ATP-AMP transphosphorylase | Adenylate kinase 3-like | Adenylate kinase 4 | Adenylate kinase isoenzyme 4, mitochondrial | KAD4_HUMAN
Type:
PROTEIN
Mol. Mass.:
25273.76
Organism:
Homo sapiens (Human)
Description:
ChEMBL_32194
Residue:
223
Sequence:
MASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVITRLMMSELENRRGQHWLLDGFPRTLGQAEALDKICEVDLVISLNIPFETLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPVIELYKSRGVLHQFSGTETNKIWPYVYTLFSNKITPIQSKEAY
  
Inhibitor
Name:
BDBM50010316
Synonyms:
CHEMBL3251364
Type:
Small organic molecule
Emp. Form.:
C17H28IN6O14P3
Mol. Mass.:
760.2618
SMILES:
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c(NCCCCCNC(=O)CI)ncnc12 |r|
Structure:
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