Reaction Details Report a problem with these data
Target
GTP:AMP phosphotransferase AK3, mitochondrial
Ligand
BDBM50027448
Substrate
n/a
Meas. Tech.
ChEBML_32217
Ki
1800000±n/a nM
Citation
 Hai, TT; Picker, D; Abo, M; Hampton, A Species- or isozyme-specific enzyme inhibitors. 7. Selective effects in inhibitions of rat adenylate kinase isozymes by adenosine 5'-phosphate derivatives. J Med Chem 25:806-12 (1982) [PubMed]  Article 
Target
Name:
GTP:AMP phosphotransferase AK3, mitochondrial
Synonyms:
AK 3 | Adenylate kinase 3 | Adenylate kinase 3 alpha like 1 | Adenylate kinase 3 alpha-like 1 | Ak3 | Ak3l1 | Akl3l | GTP:AMP phosphotransferase mitochondrial | KAD3_RAT
Type:
PROTEIN
Mol. Mass.:
25443.58
Organism:
Rattus norvegicus
Description:
ChEMBL_1340551
Residue:
227
Sequence:
MGASGRLLRAVIMGAPGSGKGTGSSRITKHFELKHLSSGDLLRQNMLQGTEIAVLAKSFIDQGKLIPDDDMTRLALHELKNLTQCSWLLDGFPRTLPQAEALDRVYQIDTVINLNVPFEVIKLRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEPVLQYYQKKGVLETFSGTETNKIRPHVYSFLQMKVPETIQKASVTP
  
Inhibitor
Name:
BDBM50027448
Synonyms:
CHEMBL3143581 | Phosphoric acid mono-[6-(6-amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl] ester
Type:
Small organic molecule
Emp. Form.:
C13H18N5O7P
Mol. Mass.:
387.2851
SMILES:
CC1(C)O[C@@H]2[C@@H](COP(O)(O)=O)O[C@H]([C@@H]2O1)n1cnc2c(N)ncnc12 |r|
Structure:
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