Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50367265
Substrate
n/a
Meas. Tech.
ChEMBL_29631 (CHEMBL636648)
Ki
0.850000±n/a nM
Citation
 Jacobson, KA; Kirk, KL; Padgett, WL; Daly, JW Functionalized congeners of adenosine: preparation of analogues with high affinity for A1-adenosine receptors. J Med Chem 28:1341-6 (1985) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50367265
Synonyms:
BDBM50396917 | CHEMBL1512545 | CHEMBL603401
Type:
Small organic molecule
Emp. Form.:
C28H32N8O6
Mol. Mass.:
576.6037
SMILES:
NCCNC(=O)Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4n(cnc34)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)cc2)cc1
Structure:
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