Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50367266
Substrate
n/a
Meas. Tech.
ChEBML_29631
Ki
18±n/a nM
Citation
 Jacobson, KA; Kirk, KL; Padgett, WL; Daly, JW Functionalized congeners of adenosine: preparation of analogues with high affinity for A1-adenosine receptors. J Med Chem 28:1341-6 (1985) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50367266
Synonyms:
CHEMBL605043
Type:
Small organic molecule
Emp. Form.:
C30H30F3N7O8
Mol. Mass.:
673.5965
SMILES:
COC(=O)C(Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4n(cnc34)C3O[C@H](CO)[C@@H](O)[C@H]3O)cc2)cc1)NC(=O)C(F)(F)F |r|
Structure:
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