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Target
Mu-type opioid receptor
Ligand
BDBM50021322
Substrate
n/a
Meas. Tech.
ChEMBL_139015 (CHEMBL744611)
Kd
6.2±n/a nM
Citation
 Cheng, A; Uyeno, E; Polgar, W; Toll, L; Lawson, JA; DeGraw, JI; Loew, G; Camerman, A; Camerman, N N-substituent modulation of opiate agonist/antagonist activity in resolved 3-methyl-3-(m-hydroxyphenyl)piperidines. J Med Chem 29:531-7 (1986) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44503.11
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:
398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50021322
Synonyms:
3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol:hydrochloricacid | CHEMBL150967
Type:
Small organic molecule
Emp. Form.:
C20H25NO
Mol. Mass.:
295.4186
SMILES:
CC1(CCCN(CCc2ccccc2)C1)c1cccc(O)c1
Structure:
Search PDB for entries with ligand similarity: