Target
Delta-type opioid receptor
Ligand
BDBM50021324
Substrate
n/a
Meas. Tech.
ChEMBL_146781 (CHEMBL754443)
Kd
2700±n/a nM
Citation
 Cheng, AUyeno, EPolgar, WToll, LLawson, JADeGraw, JILoew, GCamerman, ACamerman, N N-substituent modulation of opiate agonist/antagonist activity in resolved 3-methyl-3-(m-hydroxyphenyl)piperidines. J Med Chem 29:531-7 (1986) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40465.04
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor.
Residue:
372
Sequence:
MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50021324
Synonyms:
3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-phenol | 3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-phenol:hydrochloricacid | CHEMBL346163
Type:
Small organic molecule
Emp. Form.:
C16H23NO
Mol. Mass.:
245.3599
SMILES:
CC1(CCCN(CC2CC2)C1)c1cccc(O)c1
Structure:
Search PDB for entries with ligand similarity: