Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50367495
Substrate
n/a
Meas. Tech.
ChEBML_28964
IC50
19±n/a nM
Citation
 Kwatra, MM; Leung, E; Hosey, MM; Green, RD N6-phenyladenosines: pronounced effect of phenyl substituents on affinity for A2 adenosine receptors. J Med Chem 30:954-6 (1987) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_CHICK | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36337.19
Organism:
Chick
Description:
ADENOSINE A1 ADORA1 Chick::P49892
Residue:
324
Sequence:
MAQSVTAFQAAYISIEVLIALVSVPGNILVIWAVKMNQALRDATFCFIVSLAVADVAVGALVIPLAIIINIGPQTEFYSCLMMACPVLILTESSILALLAIAVDRYLRVKIPVRYKSVVTPRRAAVAIACCWIVSFLVGLTPMFGWNNLNKVLGTRDLNVSHSEFVIKCQFETVISMEYMVYFNFFVWVLPPLLLMLLIYLEVFNLIRTQLNKKVSSSSNDPQKYYGKELKIAKSLALVLFLFALSWLPLHILNCITLFCPSCKTPHILTYIAIFLTHGNSAMNPIVYAFRIKKFRTAFLQIWNQYFCCKTNKSSSSSTAETVN
  
Inhibitor
Name:
BDBM50367495
Synonyms:
CHEMBL607951
Type:
Small organic molecule
Emp. Form.:
C16H16IN5O4
Mol. Mass.:
469.2338
SMILES:
OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(Nc3cccc(I)c3)ncnc12 |r|
Structure:
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