Reaction Details Report a problem with these data
Target
Adenosine deaminase
Ligand
BDBM50011566
Substrate
n/a
Meas. Tech.
ChEBML_30803
Ki
400000±n/a nM
Citation
 Cristalli, G; Franchetti, P; Grifantini, M; Vittori, S; Lupidi, G; Riva, F; Bordoni, T; Geroni, C; Verini, MA Adenosine deaminase inhibitors. Synthesis and biological activity of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine. J Med Chem 31:390-3 (1988) [PubMed]  Article 
Target
Name:
Adenosine deaminase
Synonyms:
ADA | ADA_BOVIN | Adenosine aminohydrolase
Type:
Enzyme
Mol. Mass.:
40910.44
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
363
Sequence:
MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPEFLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAIDLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYHTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIFKSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAEQCL
  
Inhibitor
Name:
BDBM50011566
Synonyms:
3-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-nonan-2-ol | CHEMBL18659
Type:
Small organic molecule
Emp. Form.:
C15H24N4O
Mol. Mass.:
276.3773
SMILES:
CCCCCCC(C(C)O)n1ccc2c(N)ncnc12
Structure:
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