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Target
Mu-type opioid receptor
Ligand
BDBM50016832
Substrate
n/a
Meas. Tech.
ChEBML_147195
Ki
1800±n/a nM
Citation
 Bryan, WM; Callahan, JF; Codd, EE; Lemieux, C; Moore, ML; Schiller, PW; Walker, RF; Huffman, WF Cyclic enkephalin analogues containing alpha-amino-beta-mercapto-beta,beta-pentamethylenepropionic acid at positions 2 or 5. J Med Chem 32:302-4 (1989) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44503.11
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:
398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50016832
Synonyms:
19-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-13-benzyl-12,15,18-trioxo-7,8-dithia-11,14,17-triaza-spiro[5.13]nonadecane-10-carboxylic acid | CHEMBL2370369
Type:
Small organic molecule
Emp. Form.:
C31H39N5O7S2
Mol. Mass.:
657.801
SMILES:
N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CSSC11CCCCC1)C(O)=O
Structure:
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