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TargetPhenylethanolamine N-methyltransferase
LigandBDBM50020509
Substrate/Competitorn/a
Meas. Tech.ChEBML_152563
Ki 228000±n/a nM
Citation Ye, QHGrunewald, GL Conformationally restricted and conformationally defined tyramine analogues as inhibitors of phenylethanolamine N-methyltransferase. J Med Chem32:478-86 (1989) [PubMed]  Article
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Phenylethanolamine N-methyltransferase
Name:Phenylethanolamine N-methyltransferase
Synonyms:Noradrenaline N-methyltransferase | PNMTase
Type:Enzyme
Mol. Mass.:30916.97
Organism:Bos taurus (bovine)
Description:n/a
Residue:283
Sequence:
MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
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  Blast E-value cutoff:
BDBM50020509
NameBDBM50020509
Synonyms:7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine | CHEMBL422274
TypeSmall organic molecule
Emp. Form.C11H15NO
Mol. Mass.177.2429
SMILESCOc1ccc2CCC(N)Cc2c1
Structure
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n/a