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Target
Gastricsin
Ligand
BDBM50017486
Substrate
n/a
Meas. Tech.
ChEBML_154148
Ki
3±n/a nM
Citation
 Harbeson, SL; Rich, DH Inhibition of aminopeptidases by peptides containing ketomethylene and hydroxyethylene amide bond replacements. J Med Chem 32:1378-92 (1989) [PubMed]  Article 
Target
Name:
Gastricsin
Synonyms:
Gastricsin | PEPC_RAT | Pepsinogen C | Pgc
Type:
PROTEIN
Mol. Mass.:
42814.23
Organism:
Rattus norvegicus
Description:
ChEMBL_154148
Residue:
392
Sequence:
MKWMVVALLCLPLLEASLLRVPLRKMKSIRETMKEQGVLKDFLKTHKYDPGQKYHFGNFGDYSVLYEPMAYMDASYFGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQSEACTTHARFNPSKSSTYYTEGQTFSLQYGTGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPGLSSGGATTALQGMLGEGALSQPLFGVYLGSQQGSNGGQIVFGGVDKNLYTGEITWVPVTQELYWQITIDDFLIGDQASGWCSSQGCQGIVDTGTSLLVMPAQYLSELLQTIGAQEGEYGEYFVSCDSVSSLPTLSFVLNGVQFPLSPSSYIIQEDNFCMVGLESISLTSESGQPLWILGDVFLRSYYAIFDMGNNKVGLATSV
  
Inhibitor
Name:
BDBM50017486
Synonyms:
2-(2-{4-Hydroxy-2,7-dimethyl-5-[3-methyl-2-(3-methyl-butyrylamino)-butyrylamino]-octanoylamino}-propionylamino)-butyric acid | CHEMBL424222
Type:
Small organic molecule
Emp. Form.:
C27H50N4O7
Mol. Mass.:
542.7085
SMILES:
CCC(NC(=O)[C@H](C)NC(=O)[C@H](C)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(O)=O
Structure:
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