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Target
Gastricsin
Ligand
BDBM50017485
Substrate
n/a
Meas. Tech.
ChEBML_154148
Ki
3±n/a nM
Citation
 Harbeson, SL; Rich, DH Inhibition of aminopeptidases by peptides containing ketomethylene and hydroxyethylene amide bond replacements. J Med Chem 32:1378-92 (1989) [PubMed]  Article 
Target
Name:
Gastricsin
Synonyms:
Gastricsin | PEPC_RAT | Pepsinogen C | Pgc
Type:
PROTEIN
Mol. Mass.:
42814.23
Organism:
Rattus norvegicus
Description:
ChEMBL_154148
Residue:
392
Sequence:
MKWMVVALLCLPLLEASLLRVPLRKMKSIRETMKEQGVLKDFLKTHKYDPGQKYHFGNFGDYSVLYEPMAYMDASYFGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQSEACTTHARFNPSKSSTYYTEGQTFSLQYGTGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPGLSSGGATTALQGMLGEGALSQPLFGVYLGSQQGSNGGQIVFGGVDKNLYTGEITWVPVTQELYWQITIDDFLIGDQASGWCSSQGCQGIVDTGTSLLVMPAQYLSELLQTIGAQEGEYGEYFVSCDSVSSLPTLSFVLNGVQFPLSPSSYIIQEDNFCMVGLESISLTSESGQPLWILGDVFLRSYYAIFDMGNNKVGLATSV
  
Inhibitor
Name:
BDBM50017485
Synonyms:
1N-[1-isopentylcarbamoyl-(1S)-ethyl]-4-[1-(1-amino-1-methylpropylcarboxamido)-2-methyl-(1S)-propylcarboxamido]-3-hydroxy-6-methyl-(3S,4S)-heptanamide | 3-Hydroxy-6-methyl-4-[3-methyl-2-(3-methyl-butyrylamino)-butyrylamino]-heptanoic acid [1-(3-methyl-butylcarbamoyl)-ethyl]-amide | CHEMBL28738
Type:
Small organic molecule
Emp. Form.:
C26H50N4O5
Mol. Mass.:
498.699
SMILES:
CC(C)CCNC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C
Structure:
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