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Target
Beta-2 adrenergic receptor
Ligand
BDBM50010838
Substrate
n/a
Meas. Tech.
ChEMBL_37835 (CHEMBL876539)
IC50
26000±n/a nM
Citation
 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Synthesis of novel (aryloxy)propanolamines and related compounds possessing both class II and class III antiarrhythmic activity. J Med Chem 33:2883-91 (1990) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2_CANLF
Type:
PROTEIN
Mol. Mass.:
46593.67
Organism:
Canis familiaris
Description:
ChEMBL_56504
Residue:
415
Sequence:
MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50010838
Synonyms:
CHEMBL100624 | N-{4-[2-Hydroxy-3-(4-imidazol-1-yl-benzylamino)-propoxy]-phenyl}-methanesulfonamide
Type:
Small organic molecule
Emp. Form.:
C20H24N4O4S
Mol. Mass.:
416.494
SMILES:
CS(=O)(=O)Nc1ccc(OCC(O)CNCc2ccc(cc2)-n2ccnc2)cc1
Structure:
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