Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM50010840
Substrate
n/a
Meas. Tech.
ChEBML_37835
IC50
510±n/a nM
Citation
 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Synthesis of novel (aryloxy)propanolamines and related compounds possessing both class II and class III antiarrhythmic activity. J Med Chem 33:2883-91 (1990) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2_CANLF
Type:
PROTEIN
Mol. Mass.:
46593.67
Organism:
Canis familiaris
Description:
ChEMBL_56504
Residue:
415
Sequence:
MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50010840
Synonyms:
1-{2-[4-(3H-Imidazol-1-yl)-phenoxy]-ethylamino}-3-m-tolyloxy-propan-2-ol | CHEMBL421005
Type:
Small organic molecule
Emp. Form.:
C21H25N3O3
Mol. Mass.:
367.4415
SMILES:
Cc1cccc(OCC(O)CNCCOc2ccc(cc2)-n2ccnc2)c1
Structure:
Search PDB for entries with ligand similarity: