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TargetAlpha-1A adrenergic receptor
LigandBDBM50010874
Substrate/Competitorn/a
Meas. Tech.ChEBML_88911
IC50 100±n/a nM
Citation Yardley, JPHusbands, GEStack, GButch, JBicksler, JMoyer, JAMuth, EAAndree, TFletcher, HJames, MN 2-Phenyl-2-(1-hydroxycycloalkyl)ethylamine derivatives: synthesis and antidepressant activity. J Med Chem33:2899-905 (1990) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-1A adrenergic receptor
Name:Alpha adrenergic receptor 1A and 1B
Synonyms:Adrenaline | Adrenaline 1 | Alpha-1 adrenoreceptor | adrenergic Alpha1A
Type:Protein
Mol. Mass.:51620.15
Organism:Rattus norvegicus (Rat)
Description:P43140
Residue:466
Sequence:
MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
VPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTL
HPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACT
TARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
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  Blast E-value cutoff:
BDBM50010874
NameBDBM50010874
Synonyms:1-(1-(4-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol | 1-[1-(4-Chloro-phenyl)-2-dimethylamino-ethyl]-cyclohexanol (HCl) | CHEMBL420644
TypeSmall organic molecule
Emp. Form.C16H24ClNO
Mol. Mass.281.821
SMILESCN(C)CC(c1ccc(Cl)cc1)C1(O)CCCCC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a