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Target
Alpha-1A adrenergic receptor
Ligand
BDBM50010890
Substrate
n/a
Meas. Tech.
ChEBML_88911
IC50
>10000±n/a nM
Citation
 Yardley, JP; Husbands, GE; Stack, G; Butch, J; Bicksler, J; Moyer, JA; Muth, EA; Andree, T; Fletcher, H; James, MN 2-Phenyl-2-(1-hydroxycycloalkyl)ethylamine derivatives: synthesis and antidepressant activity. J Med Chem 33:2899-905 (1990) [PubMed]  Article 
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
ADA1A_RAT | Adra1a | Adra1c | Alpha-1 adrenoreceptor | Alpha-1A adrenoceptor | Alpha-1A adrenoreceptor | Alpha-1C adrenergic receptor | adrenergic Alpha1A
Type:
Protein
Mol. Mass.:
51620.15
Organism:
Rattus norvegicus (Rat)
Description:
P43140
Residue:
466
Sequence:
MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACTTARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
  
Inhibitor
Name:
BDBM50010890
Synonyms:
1-[1-(4-Methoxy-phenyl)-2-piperidin-1-yl-ethyl]-cyclohexanol(HCl) | CHEMBL328839
Type:
Small organic molecule
Emp. Form.:
C20H31NO2
Mol. Mass.:
317.4656
SMILES:
COc1ccc(cc1)C(CN1CCCCC1)C1(O)CCCCC1
Structure:
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