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Target
D(2) dopamine receptor
Ligand
BDBM50007129
Substrate
n/a
Meas. Tech.
ChEMBL_62397 (CHEMBL672952)
Ki
807±n/a nM
Citation
 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW (1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist. J Med Chem 33:2948-50 (1990) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50007129
Synonyms:
(1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol | 1-Aminomethyl-3-phenyl-isochroman-5,6-diol | A-70108 | CHEMBL86931
Type:
Small organic molecule
Emp. Form.:
C16H17NO3
Mol. Mass.:
271.3111
SMILES:
NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: