Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM50368077
Substrate
n/a
Meas. Tech.
ChEBML_213083
Ki
1000±n/a nM
Citation
 Tidwell, RR; Jones, SK; Geratz, JD; Ohemeng, KA; Cory, M; Hall, JE Analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine) in the treatment of experimental Pneumocystis carinii pneumonia. J Med Chem 33:1252-7 (1990) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1
Type:
Enzyme
Mol. Mass.:
26557.80
Organism:
Homo sapiens (Human)
Description:
P07477
Residue:
247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
  
Inhibitor
Name:
BDBM50368077
Synonyms:
CHEMBL3216901 | CHEMBL493336
Type:
Small organic molecule
Emp. Form.:
C19H24Cl2N6O6
Mol. Mass.:
503.336
SMILES:
Cl.Cl.NC(=N)c1ccc(OCCCCCOc2ccc(cc2[N+]([O-])=O)C(N)=N)c(c1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: