Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50010733
Substrate
n/a
Meas. Tech.
ChEMBL_58703 (CHEMBL672048)
IC50
230±n/a nM
Citation
 Claudi, F; Cardellini, M; Cingolani, GM; Piergentili, A; Peruzzi, G; Balduini, W Synthesis and dopamine receptor affinities of 2-(4-fluoro-3- hydroxyphenyl)ethylamine and N-substituted derivatives. J Med Chem 33:2408-12 (1990) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50010733
Synonyms:
5-[2-(Ethyl-phenethyl-amino)-ethyl]-2-fluoro-phenol; hydrobromide | CHEMBL540546
Type:
Small organic molecule
Emp. Form.:
C18H22FNO
Mol. Mass.:
287.3718
SMILES:
CCN(CCc1ccccc1)CCc1ccc(F)c(O)c1
Structure:
Search PDB for entries with ligand similarity: