Reaction Details Report a problem with these data
Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM73402
Substrate
n/a
Meas. Tech.
ChEBML_139068
Ki
1.2±n/a nM
Citation
 Hudkins, RL; DeHaven-Hudkins, DL; Stubbins, JF Muscarinic receptor binding profile of para-substituted caramiphen analogues. J Med Chem 34:2984-9 (1991) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.46
Organism:
RAT
Description:
P08482
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM73402
Synonyms:
1-Phenyl-cyclopentanecarboxylic acid 2-diethylamino-ethyl ester | 1-phenyl-1-cyclopentanecarboxylic acid 2-(diethylamino)ethyl ester;hydrochloride | 1-phenylcyclopentanecarboxylic acid 2-(diethylamino)ethyl ester;hydrochloride | 2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate;hydrochloride | 2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate hydrochloride | CARAMIPHEN | CHEMBL61946 | MLS000532799 | SMR000140237 | cid_67173
Type:
Small organic molecule
Emp. Form.:
C18H27NO2
Mol. Mass.:
289.4125
SMILES:
CCN(CC)CCOC(=O)C1(CCCC1)c1ccccc1
Structure:
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