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Target
Thromboxane A2 receptor
Ligand
BDBM50452544
Substrate
n/a
Meas. Tech.
ChEBML_210105
IC50
36±n/a nM
Citation
 Mais, DE; Bowling, NL; True, TA; Naka, M; Morinelli, TA; Oatis, JE; Hamanaka, N; Halushka, PV Novel synthesis and biochemical properties of an [125I]-labeled photoaffinity probe for thromboxane A2/prostaglandin H2 receptors. J Med Chem 34:1511-4 (1991) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50452544
Synonyms:
CHEMBL2448578
Type:
Small organic molecule
Emp. Form.:
C21H29N3O4
Mol. Mass.:
387.4727
SMILES:
[H][C@]12CC[C@@]([H])(O1)[C@H](C\C=C/CCCC(O)=O)[C@@H]2CNNC(=O)Nc1ccccc1 |r,THB:18:17:6:2.3|
Structure:
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