Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50006967
Substrate
n/a
Meas. Tech.
ChEMBL_201280 (CHEMBL805614)
Ki
9.5±n/a nM
Citation
 Glennon, RAIsmaiel, AMSmith, JDYousif, Mel-Ashmawy, MHerndon, JLFischer, JBHowie, KJServer, AC Binding of substituted and conformationally restricted derivatives of N-(3-phenyl-n-propyl)-1-phenyl-2-aminopropane at sigma-receptors. J Med Chem 34:1855-9 (1991) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Homo sapiens (Human)
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50006967
Synonyms:
CHEMBL53170 | [2-(4-Methoxy-phenyl)-1-methyl-ethyl]-(3-phenyl-propyl)-amine
Type:
Small organic molecule
Emp. Form.:
C19H25NO
Mol. Mass.:
283.4079
SMILES:
COc1ccc(CC(C)NCCCc2ccccc2)cc1
Structure:
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