Reaction Details Report a problem with these data
Target
S-methyl-5'-thioadenosine phosphorylase
Ligand
BDBM50368299
Substrate
n/a
Meas. Tech.
ChEBML_103126
Ki
1900±n/a nM
Citation
 Sufrin, JR; Spiess, AJ; Kramer, DL; Libby, PR; Miller, JT; Bernacki, RJ; Lee, YH; Borchardt, RT; Porter, CW Targeting 5'-deoxy-5'-(methylthio)adenosine phosphorylase by 5'-haloalkyl analogues of 5'-deoxy-5'-(methylthio)adenosine. J Med Chem 34:2600-6 (1991) [PubMed]  Article 
Target
Name:
S-methyl-5'-thioadenosine phosphorylase
Synonyms:
MTAP_MOUSE | Mtap | S-methyl-5-thioadenosine phosphorylase
Type:
PROTEIN
Mol. Mass.:
31064.59
Organism:
Mus musculus
Description:
ChEMBL_12784
Residue:
283
Sequence:
MASGSACTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDMVIIDQFIDRTSLRPQTFYDGSHCSARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTIVTIEGPRFSSRAESLIFRTWGADVVNMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDGVLKTMKENANKAKSLLLTTIPQIGSMEWSETLRNLKNMAQFSVLPPRH
  
Inhibitor
Name:
BDBM50368299
Synonyms:
CHEMBL608305
Type:
Small organic molecule
Emp. Form.:
C12H17N5O3S
Mol. Mass.:
311.36
SMILES:
CCSC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Structure:
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