Reaction Details Report a problem with these data
Target
S-methyl-5'-thioadenosine phosphorylase
Ligand
BDBM50368302
Substrate
n/a
Meas. Tech.
ChEBML_103126
Ki
3100±n/a nM
Citation
 Sufrin, JR; Spiess, AJ; Kramer, DL; Libby, PR; Miller, JT; Bernacki, RJ; Lee, YH; Borchardt, RT; Porter, CW Targeting 5'-deoxy-5'-(methylthio)adenosine phosphorylase by 5'-haloalkyl analogues of 5'-deoxy-5'-(methylthio)adenosine. J Med Chem 34:2600-6 (1991) [PubMed]  Article 
Target
Name:
S-methyl-5'-thioadenosine phosphorylase
Synonyms:
MTAP_MOUSE | Mtap | S-methyl-5-thioadenosine phosphorylase
Type:
PROTEIN
Mol. Mass.:
31064.59
Organism:
Mus musculus
Description:
ChEMBL_12784
Residue:
283
Sequence:
MASGSACTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDMVIIDQFIDRTSLRPQTFYDGSHCSARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTIVTIEGPRFSSRAESLIFRTWGADVVNMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDGVLKTMKENANKAKSLLLTTIPQIGSMEWSETLRNLKNMAQFSVLPPRH
  
Inhibitor
Name:
BDBM50368302
Synonyms:
CHEMBL609198
Type:
Small organic molecule
Emp. Form.:
C12H16FN5O3S
Mol. Mass.:
329.351
SMILES:
Nc1ncnc2n(cnc12)C1O[C@H](CSCCF)[C@@H](O)[C@H]1O |r|
Structure:
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