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Target
Cholecystokinin receptor type A
Ligand
BDBM50008190
Substrate
n/a
Meas. Tech.
ChEBML_50058
IC50
33300±n/a nM
Citation
 Makovec, F; Peris, W; Revel, L; Giovanetti, R; Mennuni, L; Rovati, LC Structure-antigastrin activity relationships of new (R)-4-benzamido-5-oxopentanoic acid derivatives. J Med Chem 35:28-38 (1992) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50008190
Synonyms:
4-(2-Adamantan-1-yl-ethylcarbamoyl)-4-(3-chloro-benzoylamino)-butyric acid | CHEMBL125874
Type:
Small organic molecule
Emp. Form.:
C24H31ClN2O4
Mol. Mass.:
446.967
SMILES:
OC(=O)CCC(NC(=O)c1cccc(Cl)c1)C(=O)NCCC12CC3CC(CC(C3)C1)C2 |TLB:28:27:30:23.22.24,28:23:30:27.29.26,24:25:29:23.22.28,THB:24:23:29:25.30.26|
Structure:
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