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Target
Protein-L-isoaspartate(D-aspartate) O-methyltransferase
Ligand
BDBM50378739
Substrate
n/a
Meas. Tech.
ChEBML_161419
Ki
126000±n/a nM
Citation
 Barton, DH; Géro, SD; Lawrence, F; Robert-Gero, M; Quiclet-Sire, B; Samadi, M Total synthesis of uracil analogues of sinefungin. J Med Chem 35:63-7 (1992) [PubMed]  Article 
Target
Name:
Protein-L-isoaspartate(D-aspartate) O-methyltransferase
Synonyms:
PCMT1 | PIMT_HUMAN | Protein-beta-aspartate methyltransferase
Type:
PROTEIN
Mol. Mass.:
24639.13
Organism:
Homo sapiens (Human)
Description:
ChEMBL_161420
Residue:
227
Sequence:
MAWKSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKCNPYMDSPQSIGFQATISAPHMHAYALELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSVNNVRKDDPTLLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGNQMLEQYDKLQDGSIKMKPLMGVIYVPLTDKEKQWSRWK
  
Inhibitor
Name:
BDBM50378739
Synonyms:
SINEFUNGIN | jm2c00120, Sinefungin
Type:
Small organic molecule
Emp. Form.:
C15H23N7O5
Mol. Mass.:
381.387
SMILES:
N[C@@H](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Structure:
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