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Target
Mu-type opioid receptor
Ligand
BDBM50001038
Substrate
n/a
Meas. Tech.
ChEBML_146540
Ki
11±n/a nM
Citation
 Carroll, FI; Abraham, P; Parham, K; Bai, X; Zhang, X; Brine, GA; Mascarella, SW; Martin, BR; May, EL; Sauss, C Enantiomeric N-substituted N-normetazocines: a comparative study of affinities at sigma, PCP, and mu opioid receptors. J Med Chem 35:2812-8 (1992) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44503.11
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:
398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50001038
Synonyms:
6,11-Dimethyl-3-(3-methyl-butyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol | CHEMBL2367794
Type:
Small organic molecule
Emp. Form.:
C15H21NO
Mol. Mass.:
231.3333
SMILES:
[H][C@]12Cc3ccc(O)cc3[C@@](C)(CCN1C)[C@H]2C |THB:8:9:16:14.12.13,15:14:16:9.3.2|
Structure:
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