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TargetHuman rhinovirus A protease
LigandBDBM50004783
Substrate/Competitorn/a
Meas. Tech.ChEBML_158058
IC50 550±n/a nM
Citation DeCamp, DLBabé, LMSalto, RLucich, JLKoo, MSKahl, SBCraik, CS Specific inhibition of HIV-1 protease by boronated porphyrins. J Med Chem35:3426-8 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Human rhinovirus A protease
Name:Human rhinovirus A protease
Synonyms:Human rhinovirus B 3A protease
Type:PROTEIN
Mol. Mass.:44361.04
Organism:Human rhinovirus B
Description:ChEMBL_158953
Residue:401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50004783
NameBDBM50004783
Synonyms:3-[18-(2-Carboxy-ethyl)-8,13-bis-(1,2-diacetoxy-ethyl)-3,7,12,17-tetramethyl-22,24-dihydro-porphin-2-yl]-propionic acid | CHEMBL408667
TypeSmall organic molecule
Emp. Form.C54H54N4O12
Mol. Mass.951.0262
SMILESCc1c(CCC(O)=O)c2cc3nc(cc4[nH]c(cc5[nH]c(cc1n2)c(C)c5C(COC(=O)C1=CCC1)OC(=O)C1=CCC1)c(C)c4C(COC(=O)C1=CCC1)OC(=O)C1=CCC1)c(C)c3CCC(O)=O |t:35,43,57,65|
Structure
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