Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50368426
Substrate
n/a
Meas. Tech.
ChEBML_157563
Ki
2.5±n/a nM
Citation
 Rich, DH; Prasad, JV; Sun, CQ; Green, J; Mueller, R; Houseman, K; MacKenzie, D; Malkovsky, M New hydroxyethylamine HIV protease inhibitors that suppress viral replication. J Med Chem 35:3803-12 (1992) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50368426
Synonyms:
CHEMBL1790892 | CHEMBL3349502
Type:
Small organic molecule
Emp. Form.:
C41H55N7O8
Mol. Mass.:
773.9175
SMILES:
[H][C@@](O)(CN1CCCC1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)OC)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1
Structure:
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