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Target
Type-1 angiotensin II receptor B
Ligand
BDBM50406795
Substrate
n/a
Meas. Tech.
ChEMBL_217980 (CHEMBL824099)
Ki
9±n/a nM
Citation
 Atwal, KS; Ahmed, SZ; Bird, JE; Delaney, CL; Dickinson, KE; Ferrara, FN; Hedberg, A; Miller, AV; Moreland, S; O'Reilly, BC Dihydropyrimidine angiotensin II receptor antagonists. J Med Chem 35:4751-63 (1993) [PubMed]  Article 
Target
Name:
Type-1 angiotensin II receptor B
Synonyms:
AGTRB_RAT | AT3 | Agtr1 | Agtr1b | Angiotensin II AT1B | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | At1b | Type-1B angiotensin II receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40929.44
Organism:
RAT
Description:
Angiotensin II AT1B 0 RAT::P29089
Residue:
359
Sequence:
MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
  
Inhibitor
Name:
BDBM50406795
Synonyms:
Cozaar | LOSARTAN POTASSIUM
Type:
Small organic molecule
Emp. Form.:
C22H22ClN6O
Mol. Mass.:
421.903
SMILES:
CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nn[n-]n1
Structure:
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