Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50008416
Substrate
n/a
Meas. Tech.
ChEMBL_29307 (CHEMBL640368)
Ki
2±n/a nM
Citation
 Jacobson, KA; van Galen, PJ; Williams, M Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. J Med Chem 35:407-22 (1992) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50008416
Synonyms:
8-Cyclohexyl-1,3,7-trimethyl-3,7-dihydro-purine-2,6-dione | CHEMBL281811
Type:
Small organic molecule
Emp. Form.:
C14H20N4O2
Mol. Mass.:
276.3342
SMILES:
Cn1c(nc2n(C)c(=O)n(C)c(=O)c12)C1CCCCC1
Structure:
Search PDB for entries with ligand similarity: