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Target
D(2) dopamine receptor
Ligand
BDBM50001972
Substrate
n/a
Meas. Tech.
ChEBML_62421
Ki
924±n/a nM
Citation
 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Dopaminergic and serotonergic activities of imidazoquinolinones and related compounds. J Med Chem 35:1076-92 (1992) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50001972
Synonyms:
5-Dipropylamino-1-methyl-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one | CHEMBL12515
Type:
Small organic molecule
Emp. Form.:
C17H25N3O
Mol. Mass.:
287.3999
SMILES:
CCCN(CCC)C1Cc2cccc3n(C)c(=O)n(C1)c23
Structure:
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