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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM50368601
Substrate/Competitorn/a
Meas. Tech.ChEMBL_159483
IC50 3.1±n/a nM
Citation Tam, TFCarrière, JMacDonald, DCastelhano, ALPliura, DHDewdney, NJThomas, EMBach, CBarnett, JChan, H Intriguing structure-activity relations underlie the potent inhibition of HIV protease by norstatine-based peptides. J Med Chem35:1318-20 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50368601
NameBDBM50368601
Synonyms:CHEMBL1794048 | CHEMBL3349509
TypeSmall organic molecule
Emp. Form.C39H54N6O10
Mol. Mass.766.8803
SMILESCC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CC(N)=O)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)OC
Structure
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