Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM50005890
Substrate
n/a
Meas. Tech.
ChEBML_45341
IC50
55000±n/a nM
Citation
 Zembower, DE; Kam, CM; Powers, JC; Zalkow, LH Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G. J Med Chem 35:1597-605 (1992) [PubMed]  Article 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM50005890
Synonyms:
1,8-Dihydroxy-2-methyl-anthraquinone | CHEMBL40849
Type:
Small organic molecule
Emp. Form.:
C15H10O4
Mol. Mass.:
254.2375
SMILES:
Cc1ccc2C(=O)c3cccc(O)c3C(=O)c2c1O
Structure:
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