Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50006001
Substrate
n/a
Meas. Tech.
ChEBML_221704
IC50
1790±n/a nM
Citation
 Wissner, A; Carroll, ML; Green, KE; Kerwar, SS; Pickett, WC; Schaub, RE; Torley, LW; Wrenn, S; Kohler, CA Analogues of platelet activating factor. 6. Mono- and bis-aryl phosphate antagonists of platelet activating factor. J Med Chem 35:1650-62 (1992) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50006001
Synonyms:
3-{3-[(3-Hexadecyloxy-2-methyl-phenoxy)-hydroxy-phosphoryloxy]-benzyl}-thiazol-3-ium | CHEMBL42848
Type:
Small organic molecule
Emp. Form.:
C33H48NO5PS
Mol. Mass.:
601.777
SMILES:
CCCCCCCCCCCCCCCCOc1cccc(OP([O-])(=O)Oc2cccc(C[n+]3ccsc3)c2)c1C
Structure:
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