Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50006070
Substrate
n/a
Meas. Tech.
ChEBML_221704
IC50
3800±n/a nM
Citation
 Wissner, A; Carroll, ML; Green, KE; Kerwar, SS; Pickett, WC; Schaub, RE; Torley, LW; Wrenn, S; Kohler, CA Analogues of platelet activating factor. 6. Mono- and bis-aryl phosphate antagonists of platelet activating factor. J Med Chem 35:1650-62 (1992) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50006070
Synonyms:
3-(3-{[3-(4-Dodecyloxy-naphthalen-1-yloxy)-2-methoxy-propoxy]-hydroxy-phosphoryloxy}-benzyl)-thiazol-3-ium | CHEMBL47531
Type:
Small organic molecule
Emp. Form.:
C36H48NO7PS
Mol. Mass.:
669.808
SMILES:
CCCCCCCCCCCCOc1ccc(OCC(COP([O-])(=O)Oc2cccc(C[n+]3ccsc3)c2)OC)c2ccccc12
Structure:
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