Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50006090
Substrate
n/a
Meas. Tech.
ChEBML_221704
IC50
9500±n/a nM
Citation
 Wissner, A; Carroll, ML; Green, KE; Kerwar, SS; Pickett, WC; Schaub, RE; Torley, LW; Wrenn, S; Kohler, CA Analogues of platelet activating factor. 6. Mono- and bis-aryl phosphate antagonists of platelet activating factor. J Med Chem 35:1650-62 (1992) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50006090
Synonyms:
3-{3-[Hydroxy-(2-methoxy-3-tetradecyloxy-phenoxy)-phosphoryloxy]-benzyl}-4,5-dimethyl-thiazol-3-ium | CHEMBL263933
Type:
Small organic molecule
Emp. Form.:
C33H48NO6PS
Mol. Mass.:
617.776
SMILES:
CCCCCCCCCCCCCCOc1cccc(OP([O-])(=O)Oc2cccc(C[n+]3csc(C)c3C)c2)c1OC
Structure:
Search PDB for entries with ligand similarity: