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TargetDopamine D2 receptor/Serotonin 2 (5-HT2) receptor
LigandBDBM50042733
Substrate/Competitorn/a
Meas. Tech.ChEBML_62882
Ki 0.033000±n/a nM
Citation Mach, RHLuedtke, RRUnsworth, CDBoundy, VANowak, PAScripko, JGElder, STJackson, JRHoffman, PLEvora, PH 18F-labeled benzamides for studying the dopamine D2 receptor with positron emission tomography. J Med Chem36:3707-20 (1994) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor
Name:Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)
Synonyms:DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DOPAMINE D2/D4 | DRD2 | Dopamine D2 receptor | Dopamine2-like
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:50931.60
Organism:Rattus norvegicus (rat)
Description:Receptor binding assays were performed using rat striatal membranes.
Residue:444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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  Blast E-value cutoff:
BDBM50042733
NameBDBM50042733
Synonyms:(9-Benzyl-3,9-diaza-bicyclo[3.3.1]non-3-yl)-(5-bromo-2,3-dimethoxy-phenyl)-methanone | CHEMBL122445
TypeSmall organic molecule
Emp. Form.C22H26ClN3O2
Mol. Mass.399.914
SMILESCOc1cc(N)c(Cl)cc1C(=O)N1CC2CCCC(C1)N2Cc1ccccc1 |TLB:10:12:15.16.17:20,21:20:15.16.17:19.12.13|
Structure
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n/a